Clinical observation on root canal therapy combined with apical curettage in the treatment of large periapical lesions
Objective:To comparatively analyze the clinical effects of root canal therapy combined with apical curet-tage versus simple root canal therapy in the treatment of large periapical lesions.Methods:A total of 88 patients with large periapical lesions treated in the hospital between January 2020 and November 2022 were selected as the study subjects.Ac-cording to different treatment methods,the patients were divided into control group(44 cases,root canal therapy)and observa-tion group(44 cases,root canal therapy combined with apical curettage).The clinical efficacy,postoperative pain and the lev-els of inflammatory factors were compared between groups.The incidence rates of complications were calculated.Results:One year of follow-up,the total clinical effective rate in the observation group(90.91％)was significantly higher than that in the control group(70.45％)(P<0.05).The time for postoperative pain disappearing in the observation group was shorter than that in the control group,and VAS score at 24 h after operation was lower than that of the control group(P<0.05).The levels of IL-6,TNF-α and CRP in gingival crevicular fluid of the two groups were comparable before treatment(P>0.05).Eight weeks after treatment,the levels of inflammatory factors mentioned above in both groups decreased,and the levels in the ob-servation group were lower than those in the control group(P<0.05).The total incidence of complications in the observation group(22.73％)was significantly lower than that in the control group(6.82％)(P<0.05).Conclusion:Root canal therapy combined with apical curettage is significantly effective in the treatment of large periapical lesions,which can alleviate pain,lower the levels of inflammatory factors,and reduce the incidence of complications.
Large periapical lesionRoot canal therapyApical curettageTherapeutic effect
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