The clinical features of urothelial carcinoma and its related factors in patients with maintenance hemodialysis (Report of 11 cases)
Objective:To investigate the urothelial carcinoma and its related factors, clinical features and prognosis in patients on maintenance dialysis. Method:We recruited 387 maintenance hemodialysis patients into a study, to investigate the incidence of urothelial carcinoma and the clinical features of the malignancies. We also used logistic regression analysis method to analyze the tumor-related factors. Result; Among the 387 maintenance hemodialysis patients, 11 cases(2. 84%) developed urothelial carcinoma. All of the patients with urothelial carcinoma presented intermittent and painless gross hematuria and exhibited refractory anemia. This group includes 8 cases with hemodialysis more than 5 years, more than 3 year; 2 cases, there was 1 case with hemodialysis in 15 monthes. All of the patients with urothelial carcinoma were treated with surgery. Whose survival time has been lasted for 6 to 48 months (average 27. 2 months). Three of them died, others have survive with no recurrence. Logistic regression analysis showed that age and the time of dialysis was the independent risk factors relating to urothelial carcinoma. Conclusion:The incidence of urothelial carcinoma was high in maintenance hemodialysis patients, the time of dialysis was an independent risk factors relating to urothelial carcinoma. Early diagnosis and operation are essential to improve their prognosis.
NETL
NSTL
万方数据
维普
