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前列腺靶向穿刺核心区域的影像特征分析

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目的:分析多参数磁共振成像(multiparametric magnetic resonance imaging,mpMRI)和超声图像认知融合靶向穿刺的核心区域的影像特征.方法:回顾性分析复旦大学附属肿瘤医院泌尿外科2022年1月-2023年10月实施前列腺认知融合靶向穿刺联合系统穿刺的255例患者临床资料.对比同期531例仅行系统穿刺患者,探讨前列腺癌及临床有意义前列腺癌(clinically significant prostate cancer,csPCa)的检出率,分析靶向穿刺的核心区域在mpMRI及超声图像上的影像特征.结果:靶向穿刺联合系统穿刺组和仅系统穿刺组患者前列腺癌检出率分别为 82. 0% (209/255)和 44. 1 % (234/531), csPCa 检出率分别为 65. 5% ( 167/255)和 32. 6% (173/531),2组患者前列腺癌检出率和csPCa检出率比较差异均有统计学意义(P<0. 05).靶向穿刺核心区域在磁共振图像上有4种不同的形态特征,分别为不规则形、类椭圆形、类圆形和弯月形,占比分别为60.0% (153/255)、18. 0%(46/255)、12. 2% (31/255)和 9. 8% (25/255),且不规则形患者的血前列腺特异性抗原(prostate specific antigen, PSA)高于其他3种(P = 0. 001).核心区域超声图像形态类似磁共振图像,但边缘较为模糊,且回声性质为低回声区的占比79. 6% (203/255),其余为等回声或高回声区.结论:正确理解前列腺磁共振图像信息以及对靶向穿刺核心区域影像特征的把握,是成功进行前列腺靶向穿刺的关键所在.
Imaging feature analysis of the core area in prostate targeted biopsy
Objective: To analyze the imaging features of the core area in cognitive fusion targeted biopsy using mpMRI and ultrasound images. Methods: A retrospective analysis was conducted on the clinical data of 255 pa-tients who underwent prostate cognitive fusion targeted biopsy with a combined system at the Urology Department of Fudan University Shanghai Cancer Center from January 2022 to October 2023. Compared with 531 patients who underwent only systematic biopsy during the same period, the detection rates of prostate cancer and clinically sig-nificant prostate cancer(csPCa) were explored, and the morphological characteristics of the core area in targeted biopsy on mpMRI and ultrasound images were evaluated and analyzed. Results: The detection rates of prostate cancer in the targeted biopsy combined with systematic biopsy group and the systematic biopsy-only group were 82. 0%(209/255) and 44. 1 % (234/531) respectively, and the csPCa detection rates were 65. 5% (167/255) and 32. 6% (173/531) respectively, with statistically significant differences in the detection rates of prostate cancer and csPCa between the two groups(P<0. 05). There were four different morphological characteristics of the targeted biopsy core area in MRI images: irregular, ellipsoid-like, round-like, and crescent, accounting for 60. 0% (153/255) , 18. 0% (46/255) , 12. 2% (31/255) , and 9. 8 % ( 25/255) respectively, and the patients with irregular shape had higher blood PSA levels than the other three groups(P = 0. 001). The morphology of the core area in ultra-sound images was similar to that in MRI images, but with more blurred edges, and the proportion of hypoechoic areas was 79. 6% (203/255) , with the rest being isoechoic or hyperechoic. Conclusion: Correct understanding of prostate MRI image information and grasping the imaging features of the targeted biopsy core area are key to the successful performance of prostate targeted biopsy.

prostate cancertargeted biopsycognitive fusionimaging features

林国文、戴波、叶定伟、朱耀、秦晓健、王弘恺

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复旦大学附属肿瘤医院泌尿外科 复旦大学上海医学院肿瘤学系(上海,200032)

前列腺癌 靶向穿刺 认知融合 影像特征

上海市医学创新研究专项基金上海市自然科学基金

23Y1190880021ZR1414500

2024

临床泌尿外科杂志
华中科技大学同济医学院附属协和医院 同济医院

临床泌尿外科杂志

CSTPCD
影响因子:0.734
ISSN:1001-1420
年,卷(期):2024.39(1)
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