Clinical and imaging features in the differential diagnosis between fat-poor angiomyolipoma and renal cell carcinoma(≤3 cm)
Objective:To evaluate the role of hematobiochemical and imaging indicators in the differential diag-nosis between small(≤3 cm)fat-poor angiomyolipoma(AML)and renal cell carcinoma(RCC).Methods:Periop-erative blood biochemistry and CT imaging data of 107 patients from September 2016 to March 2022 were ana-lyzed,including 20 fat-poor AML patients and 87 RCC patients.Univariate and multivariate logistic regression a-nalysis were used to analyze the risk factors between the two groups.The independent risk factors were selected for ROC curve analysis.Results:There were 69 males and 38 females,46 left kidneys and 61 right kidneys.Pa-tientsage was 21-76 years([52.1±12.5]years).The tumor size was 1-3 cm([2.2±0.6]cm).Between the two groups,BMI,WBC,alkaline phosphatase(ALP),low-density lipoprotein(LDL)and tumor standardized het-erogeneous ratio(SHR)were significantly decreased in the fat-poor AML group,while high density lipoprotein(HDL)was significantly increased(P＜0.05).Multivariate logistic analysis showed that BMI,HDL and SHR were independent risk factors for identifying fat-poor AML and RCC.The ROC curve showed that the threshold values of BMI,HDL and SHR were 22.374 kg/m2(sensitivity 75.0％,specificity 67.8％),1.17 mmol/L(sensi-tivity70.0％,specificity 71.9％),and 202.007(sensitivity 65.0％,specificity 63.2％),respectively.Conclu-sion:Small renal masses(≤3 cm)were more likely to be diagnosed with fat-poor AML,when SHR＜202.007,BMI＜22.374 kg/m2and HDL＞1.17 mmol/L.
万方数据
维普
