摘要
前列腺癌(prostate cancer,PCa)是发生在前列腺的上皮性恶性肿瘤,是男性泌尿生殖系统常见的恶性肿瘤.粒子植入全称为"放射性粒子植入治疗技术",是一种将125I或103Pd等含放射性的粒子按计划植入肿瘤内部以摧毁肿瘤的治疗手段.现代前列腺粒子植入治疗是一种经会阴、经直肠超声引导的技术,具有微创、损伤小、术后恢复快、最大程度地保留前列腺功能及尿道功能等优势.本文将从粒子植入的定位手段、单一治疗和联合治疗的疗效、并发症及其他相关研究等方面探讨粒子植入治疗的潜力、患者选择及未来的发展方向.
Abstract
Prostate cancer(PCa)is an epithelial malignant tumor that occurs in the prostate,and is a com-mon malignant tumor of the male genitourinary system.Particle implantation,which stands for"radioactive parti-cle implantation therapy technology"is a treatment that implants radioactive particles such as 125I or 103 Pd into the tumor as planned to destroy the tumor.Modern prostate particle implantation is a technique under the guidance of transperineal and transrectal ultrasound,which has the advantages of minimal invasion,small injury,quick post-operative recovery,and maximum preservation of the functions of prostate and urethral.This article will discuss the po-tential of particle implantation,patient selection and future development direction from the aspects of positioning means of particle implantation,efficacy of single therapy and combination therapy,complications and other related studies.
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