Association between age,TyG index and serum tPSA in patients with benign prostatic hyperplasia
Objective:To investigate the association between the triglyceride-glucose(TyG)index and total prostate-specific antigen(tPSA)in the serum of patients with benign prostatic hyperplasia(BPH).Methods:The study grouped serum tPSA based on whether it was ≥1.6 μg/L.Logistic univariate and multivariate analyses were used to assess the correlation between TyG index,age,BMI,other related biochemical indicators and tPSA in 455 patients with BPH.Results:Univariate analysis snggested that tPSA≥1.6 μg/L was positively correlated with age and negatively correlated with triglycerides,glutamic-pyruvic transaminase,total cholesterol,and TyG index.In the multivariate analysis,Model 2 adjusted for age and BMI,and Model 3 adjusted low-density lipopro-tein cholesterol based on Model 2.After these adjustments,tPSA still showed a negative correlation with TyG in-dex,and the results of the subgroup analysis remained robust with no significant interaction.Conclusion:Age and the TyG index have a certain impact on serum tPSA levels in patients with BPH.Clinically,the influence of age and TyG index should be considered when evaluating serum tPSA levels.
agetriglyceride-glucose indexbenign prostatic hyperplasiatotal prostate-specific antigencross-sectional study
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NSTL
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