The study on cell death plays an important role in tumor,from apoptosis to necroptosis to pyroptosis,and then to ferroptosis and cuproptosis.Ferroptosis,as a kind of iron-dependent programmed cell death,is characterized by lipid peroxide(LPO),reactive oxygen species(ROS)and iron accumulation.Targeted ferroptosis has received much at-tention as an alternative research strategy for the treatment of renal cell carcinoma.It is necessary to look for biomarkers related to ferroptosis to diagnose and predict the prognosis of renal cell carcinoma
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