Preliminary exploration of radical enucleation for prostate cancer
Objective:To investigate the feasibility of radical enucleation of prostate cancer in the application of localized prostate cancer.Methods:From December 2023 to March 2024,10 patients with localized prostate canc-er with prostate-specific antigen(PSA)＜20 ng/mL were screened and enrolled in Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,with a median age of 71 years,a median body mass in-dex of 25 kg/m2,and a median Gleason score of 3+4=7.On the basis of Hood technology to protect the struc-tures behind the pubic bone and near the apex of the prostate,radical enucleation of prostate cancer draws on the advantages of posterior radical prostatectomy in the exploration of the intrafascial layer and the protection of the neurovascular bundle in the neck of the prostate.Results:The median time from skin incision to skin closure was 109 minutes,and the median blood loss was 80 mL.The positive rate of resection margin was 20％,and PSA＜0.2 ng/mL was found in 90％of patients 6 weeks after surgery.Immediate urinary continence rate was 60％,and erectile preservation rates at median follow-up of 4 months were 86％(6/7).Conclusion:Radical enucleation of prostate cancer has ideal effect in immediate urinary continence and sexual function preservation,and the approach and steps are clear and concise,which is worthy of clinical reference and application.
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