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儿童睾丸良性肿瘤44例报告

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目的:总结儿童睾丸良性肿瘤的临床资料,探讨其围手术期评估的特点,提高保留睾丸手术的可及性.方法:回顾性分析2010年1月-2023年6月中山大学肿瘤防治中心收治的睾丸肿瘤患儿的临床资料,其中睾丸良性肿瘤44例.收集睾丸良性肿瘤患儿术前评估资料、术后病理结果及随访资料,统计分析其特点.结果:44例患儿中左侧17例,右侧25例,双侧2例;年龄3个月~12岁,中位年龄8岁,2岁及以下13例.其中畸胎瘤22例,表皮样囊肿18例,腺瘤2例,间皮囊肿2例.所有患儿均常规行睾丸癌肿瘤标志物检测,其中2例血清甲胎蛋白(alpha fetoprotein,AFP)升高,超声检查考虑良性,均行根治性睾丸切除术;术前超声检查提示恶性肿瘤4例,肿瘤标志物均正常范围,其中3例行根治术,1例行保留睾丸手术.共23例患儿行根治性睾丸切除术,21例患儿行保留睾丸手术.术后随访6~87个月,中位随访时间44个月.所有受访患儿均未见肿瘤复发或者残留睾丸萎缩等并发症.结论:儿童睾丸肿瘤中良性肿瘤占有较高比例,应重视儿童睾丸肿瘤围手术期评估,避免过度治疗.
Report on 44 cases of testicular benign tumors in children
Objective:To summarize the clinical data of benign testicular tumors,and explore the feasibility and effectiveness of testis-sparing surgery for testicular tumors in children.Methods:A retrospective analysis of clinical data on pediatric testicular tumors admitted to Cancer Center,Sun Yat-sen University from January 2010 to June 2023 was performed.Among them,there were 44 cases of benign testicular tumors.Preoperative evalua-tion data,postoperative pathological results,and follow-up data of patients with benign testicular tumors were collected,and analyzed.Results:Among 44 pediatric patients,there were 17 on the left side,25 on the right side,and 2 on both sides.The age range was from 3 months to 12 years old,and the median age was 8 years old.Thir-teen cases were younger than 2 years old.Among them,there were 22 cases of teratoma,18 cases of epidermoid cyst,2 cases of adenoma,and 2 cases of mesothelial cyst.All children were routinely tested for testicular cancer markers.Among them,2 cases presented with elevated serum alpha fetoprotein(AFP)level,but ultrasound ex-amination considered benign lesions.Then,both of them underwent radical orchiectomy.Preoperative ultrasound examination revealed malignant tumors in 4 patients,whose tumor markers were all within normal range.Among them,3 underwent radical surgery and 1 underwent testis-sparing surgery.A total of 23 children underwent radi-cal orchiectomy,while 21 cases underwent testis-sparing surgery.The follow-up period was 6-87 months,with a median time of 44 months.All interviewed patients did not have any complications such as tumor recurrence or residual testicular atrophy.Conclusion:Benign tumors account for a high proportion of testicular tumors in chil-dren,so perioperative evaluation of testicular tumors in children should be emphasized to avoid overtreatment.

childrentesticular tumorbenign tumorstestis-sparing surgeryperioperative evaluation

殷坤党、刘振华、李志勇、李向东、刘卓炜、秦自科、叶云林

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中山大学肿瘤防治中心泌尿外科 华南肿瘤学国家重点实验室(广州,510060)

肿瘤医学协同创新中心

中山大学肿瘤防治中心甘肃医院泌尿外科

儿童 睾丸肿瘤 良性肿瘤 保留睾丸手术 围手术期评估

2024

临床泌尿外科杂志
华中科技大学同济医学院附属协和医院 同济医院

临床泌尿外科杂志

CSTPCD
影响因子:0.734
ISSN:1001-1420
年,卷(期):2024.39(8)
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