Objective:To observe the safety of continuous monitoring of renal pelvis pressure through the ne-phrostomy channel in the treatment of upper ureteral stones with ureteroscopic lithotripsy,analyze the impact on inflammatory indicators,and provide a basis for clinical promotion of this technology.Methods:Patients with up-per ureteral stones who underwent ureteroscopic lithotripsy at First Affiliated Hospital of Bengbu Medical Univer-sity from October 2022 to December 2023 were collected.All patients were divided into an observation group and a control group based on whether they underwent percutaneous nephrostomy before surgery.The observation group was connected to a pressure measuring device through a nephrostomy tube before the surgery,and surgical treatment was performed under pressure monitoring and control in the renal pelvis during the operation.Postoper-ative temperature fluctuations of patients were observed and recorded,and changes in inflammatory indicators,in-cluding white blood cell(WBC),platelet(PLT),and C-reactive protein(CRP)were analyzed on the first day after surgery.The residual stones were evaluated by plain film of kidney-ureter-bladder(KUB)one month after surgery.Results:A total of 50 patients with stones were included,with 20 in the observation group and 30 in the control group.There was no statistically significant difference in general information between the two groups of patients(P＞0.05).There was no statistically significant difference(P＞0.05)in terms of surgical time,hospital stay,or residual stones.The incidence of postoperative fever in the observation group was lower than that in the control group,though there was no significant difference.There was no significant difference in preoperative blood WBC,PLT,or CRP levels between the two groups of patients(P＞0.05).The postoperative WBC and CRP levels were higher than preoperative levels(P＜0.05),but there was no significant difference in PLT level between preopera-tive and postoperative levels(P＞0.05).The expressions of WBC and CRP in the observation group were signifi-cantly lower than those in the control group after surgery(P＜0.05),while the PLT level was not significantly different(P＞0.05).Conclusion:Continuous monitoring of intrapelvic pressure through the nephrostomy channel can effectively control the intrapelvic pressure during ureteroscopic lithotripsy and prevent intraoperative and post-operative infections.This operation is simple and feasible,so is worthy of clinical application.
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