Leveraging volatile organic compounds in non-invasive diagnosis of bladder cancer:a systematic review
Currently a non-invasive diagnostic approach to bladder cancer is a research hotspot.Since volatile organic compounds can be products of metabolic processes,a lot of studies used analytical instruments or e-nose sensor to study urine volatilomics and proved the viability of this approach.Urine volatilomics shows great poten-tial in bladder cancer diagnosis.In future,researchers need to overcome challenges like insufficient cohort size and unadjusted confounding factors,and apply more rigorous methods for annotation of volatile organic compounds.
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