Clinical significance of retinol-binding protein in predicting postoperative ileus after radical cystectomy
Objective:To analyze the clinical value of retinol-binding protein in predicting postoperative ileus in patients with radical cystectomy and ileal conduit.Methods:The clinical data of 67 patients who underwent radical cystectomy and ileal conduit in Shaanxi Provincial People's Hospital from September 2013 to October 2022 were retrospectively analyzed.According to whether postoperative intestinal ileus occurred,the patients were divided into non-occurrence group and occurrence group,and the risk factors in postoperative ileus in patients with radical cystectomy and ileal conduit were analyzed.Results:Among 67 patients,24 patients developed ileus,and the inci-dence rate was 35.82%.Univariate analysis showed that T3-T4,cholinesterase and retinol binding protein may be the influencing factors in postoperative ileus.Multivariate analysis showed that T3-T4 staging and low level of retinol binding protein were independent risk factors in postoperative ileus in patients with radical cystectomy and ileal conduit.ROC curve combined with Youden index analysis showed that retinol binding protein<36.62 mg/L was a risk factor in postoperative intestinal obstruction.Conclusion:Retinol binding protein level may be an effec-tive clinical index to predict postoperative ileus in patients with radical cystectomy and ileal conduit.
muscle-invasive bladder cancerileusradical cystectomy and ileal conduitrisk factors