Effect of right ventricular dysfunction on early prognosis of sepsis patients under echocardiography
Objective To investigate the value of right ventricle dysfunction under echocardiography in predicting 28 d death in patients with sepsis.Methods A total of 263 patients with sepsis were divided into death group(61 cases)and survival group(202 cases)according to their survival status 28 d after admission.Baseline data and echocardiographic results were collected and compared between groups.Multivariate logistic regression analysis was used to investigate the influencing factors of 28 d death in patients with sepsis.Results The mortality rate of 263 patients with sepsis was 23.19％at 28 d after admission.The incidence of right ventricular dysfunction was 48.29％,and the mortality rate of 28 d was 67.21％.The incidence of left ventricular dysfunction was 65.02％,and the mortality rate of 28 d was 57.38％.Compared with survival group,age,acute physiology,chronic health status scoring system(APACHE Ⅱ)score and the proportion of patients with invasive mechanical ventilation,diabetes and hyperlipidemia were higher in death group,right ventricle area change fraction,tricuspid ring systolic displacement and right ventricle myocardial work index(RV-MPI)were lower in death group(P＜0.05).Multivariate logistic regression analysis showed that age≥60 years old,APACHE Ⅱ score＞15 points,mechanical ventilation and right ventricle dysfunction were all risk factors for 28 d death in sepsis patients(P＜0.05).Conclusion Left ventricular dysfunction was not associated with 28 d mortality in patients with sepsis.The mortality rate of 28 d in patients with sepsis complicated with right ventricular dysfunction was 3.159 times higher than that without sepsis.
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