伴癫痫发作重症患儿的临床及脑电图特征分析
Characteristics analysis of clinical and electroencephalography in children with severe disease accompanied by epileptic seizures
李娅娅 1王晓玲1
作者信息
- 1. 450000,河南郑州,郑州大学第一附属医院儿童重症医学病区
- 折叠
摘要
目的 探讨伴癫痫发作重症患儿的临床及脑电图特征分析.方法 回顾性分析郑州大学第一附属医院儿童重症医学病区2022年1月至2023年12月收治的74例重症患儿的临床资料,运用脑电图监测患儿的癫痫发作情况,并根据有无癫痫发作将患儿分为癫痫发作组和无癫痫发作组.分析患儿的临床特征及癫痫发作的风险因素.结果 癫痫发作组患儿的智力发育迟缓、癫痫史、监测前惊厥发作、监测时意识障碍及呼吸衰竭发生率均高于无癫痫发作组,差异有统计学意义(P＜0.05).癫痫发作组患儿脑电图的背景活动异常、发作间期放电、暴发-抑制及低电压和(或)电静息发生率均高于无癫痫发作组患儿,差异有统计学意义(P＜0.05).多因素logistic回归分析显示脑电图监测前惊厥发作、间期放电是重症患儿癫痫发作的独立危险因素(P＜0.05).结论 脑电图监测前惊厥发作及间期放电是伴癫痫发作重症患儿的独立危险因素.
Abstract
Objective To investigate the characteristics of clinical and electroencephalography in children with severe disease accompanied by epileptic seizures.Methods Retrospective analysis was conducted on the clinical data of 74 children with severe disease admitted to pediatric intensive care unit at the first affiliated hospital of Zhengzhou University from January 2022 to December 2023.Electroen-cephalography was used to monitor epileptic seizures.According to the presence or absence of epileptic seizures,the children were divided into epileptic seizure group and non-epileptic seizure group.Clinical characteristics of the children and risk factors for epileptic seizures were analyzed.Results The inci-dences of mental retardation,history of epilepsy,convulsive seizures before monitoring,disorders of consciousness during monitoring and respiratory failure were higher in epileptic seizure group than those in non-epileptic seizure group(P＜0.05).The incidences of abnormal background activity,in-terictal discharge,burst-suppression and low voltage and(or)electric silence were higher in epileptic seizure group than those in non-epileptic seizure group(P＜0.05).Multivariate logistic regression a-nalysis showed that convulsive seizures before electroencephalography monitoring and intermittent dis-charges were independent risk factors for epileptic seizures(P＜0.05).Conclusion Convulsive sei-zures before electroencephalography monitoring and intermittent discharges are independent risk fac-tors for children with severe disease accompanied by epileptic seizures.
关键词
脑电图监测/重症患儿/癫痫发作/危险因素Key words
electroencephalography monitoring/children with severe disease/epileptic seizures/risk facto引用本文复制引用
基金项目
河南省医学科技攻关项目(SBGJ202103069)
出版年
2024
NETL
NSTL
万方数据