首页|迷走神经刺激术治疗超难治性癫痫持续状态2例

迷走神经刺激术治疗超难治性癫痫持续状态2例

Vagus nerve stimulation for treatment of super-refractory status epilepticus:report of 2 cases

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目的 探究迷走神经刺激术(VNS)治疗超难治性癫痫持续状态(SRSE)的疗效.方法 纳入2例分别于2012年2月28日和2020年6月10日在首都医科大学三博脑科医院行VNS的SRSE患者,分析其临床特征及手术疗效.结果 2例患者术中情况良好,病例1于刺激器开机1周后癫痫持续状态(SE)消失,术后7年随访提示未再发生SE且癫痫发作频率减少50%;病例2于刺激器开机1个月后SE消失,术后2年随访提示未再发生SE且癫痫发作频率减少80%.结论 VNS是治疗SRSE的安全有效手段.
Objective To investigate the efficacy of vagus nerve stimulation(VNS)in the treatment of super-refractory status epilepticus(SRSE).Methods 2 patients diagnosed with SRSE,who underwent VNS on February 28,2012 and June 10,2020 in Sanbo Brain Hospital,Capital Medical University,were included to analyze their clinical characteristics and surgical efficacy respectively.Results 2 patients were in good condition intraoperatively.Case 1 had disappearance of status epilepticus(SE)1 week after the stimulator was turned on,and the 7-year postoperative follow-up suggested no recurrence of SE and 50%reduction in seizure frequency.Case 2 had disappearance of SE 1 month after the stimulator was turned on,and the 2-year postoperative follow-up revealed no recurrence of SE and an 80%reduction in seizure frequency.Conclusion VNS is a safe and effective treatment for SRSE.

super-refractory status epilepticusvagus nerve stimulationefficacy

彭鑫涛、孙卫进、马凯强、王雄飞、周健、王梦阳、王静、李天富、栾国明、关宇光

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100093 北京,首都医科大学三博脑科医院神经外科

100093 北京,首都医科大学三博脑科医院神经内科

北京市临床医学研究癫痫病重点实验室

北京脑重大疾病研究院癫痫研究所

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超难治性癫痫持续状态 迷走神经刺激术 疗效

国家重点研发计划

2021YFC2401203

2024

临床神经外科杂志
南京医科大学附属脑科医院

临床神经外科杂志

CSTPCD
影响因子:1.019
ISSN:1672-7770
年,卷(期):2024.21(3)