Objective To investigate the efficacy of vagus nerve stimulation(VNS)in the treatment of super-refractory status epilepticus(SRSE).Methods 2 patients diagnosed with SRSE,who underwent VNS on February 28,2012 and June 10,2020 in Sanbo Brain Hospital,Capital Medical University,were included to analyze their clinical characteristics and surgical efficacy respectively.Results 2 patients were in good condition intraoperatively.Case 1 had disappearance of status epilepticus(SE)1 week after the stimulator was turned on,and the 7-year postoperative follow-up suggested no recurrence of SE and 50%reduction in seizure frequency.Case 2 had disappearance of SE 1 month after the stimulator was turned on,and the 2-year postoperative follow-up revealed no recurrence of SE and an 80%reduction in seizure frequency.Conclusion VNS is a safe and effective treatment for SRSE.
super-refractory status epilepticusvagus nerve stimulationefficacy