Objective To analyze the clinical efficacy and safety of 3D printing guided percutaneous microballoon compression(PMC)and conventional PMC in the treatment of primary trigeminal neuralgia(PTN).Methods A total of 80 patients with PTN treated in the Department of Neurosurgery,Langfang Municipal People's Hospital from January 2020 to December 2022 were selected as the study objects.All patients were divided into observation group and control group with 40 cases in each group using random number table method.The control group received conventional PMC treatment,and the observation group received 3D printing guide positioning PMC treatment.The general situation of operation,immediate postoperative efficacy,pain visual analogue scale(VAS)score at different time points before and after operation,recurrence 12 months after operation and postoperative complications were compared between two groups.Results The success rate of first puncture in observation group was 97.50%,which was significantly higher than that in control group(27.50%,P<0.05).The puncture success time,total operation time,hospitalization time and hospitalization cost in observation group were significantly better than those in control group(P<0.05).The total effective rate was 97.50%in the observation group and 95.00% in the control group,the difference was not statistically significant(P>0.05).Comparison of VAS scores between two groups before surgery,1 and 2 weeks after surgery(P>0.05)showed that the VAS score of the observation group at 4 weeks after surgery was significantly lower than that of the control group(P<0.05).At12 months after operation,the recurrence rate of observation group was 5.00%,which was significantly lower than that of control group(20.00%)(P<0.05).The incidence of facial numbness,masseteric muscle weakness and herpes labialis in observation group was compared with that in control group,the difference was not statistically significant(P>0.05).Conclusions PMC with 3D printed guide plate can significantly improve the success rate of the first puncture,shorten the puncture time and the total operation time,and the immediate and long-term effect after operation are very significant.
3D printingguide plate localizationpercutaneous microballoon compressionprimary trigeminal neuralgiatreatment outcome