首页|单纯表面麻醉与静脉全身麻醉对经内镜逆行胰胆管造影术术后胰腺炎发生的影响

单纯表面麻醉与静脉全身麻醉对经内镜逆行胰胆管造影术术后胰腺炎发生的影响

扫码查看
原文链接
  • NETL
  • NSTL
  • 万方数据
目的 探讨单纯表面麻醉与静脉全身麻醉对经内镜逆行胰胆管造影术(ERCP)术后胰腺炎发生的影响.方法 2021年1月～2023年3月间在我院收治的因胰胆管疾病行ERCP病人400例,分为单纯表面麻醉组和静脉全身麻醉组,每组各200例.记录两组病人术前及术后3小时、24小时静脉血清胰淀粉酶水平及腹部症状体征,观察两组病人术后3小时、24小时发生高淀粉酶血症和术后胰腺炎的情况.结果 单纯表面麻醉组ERCP术后胰腺炎的发生率为7.5％,静脉全身麻醉组为2.0％,两组比较差异有统计学意义(P＜0.05);术后3小时静脉全身麻醉组血清胰淀粉酶水平为(198±216)U/L,单纯表面麻醉组为(379±327)U/L,两组比较差异有统计学意义(P＜0.05);术后24小时,静脉全身麻醉组血清胰淀粉酶水平为(129±98)U/L,单纯表面麻醉组为(187±156)U/L,两组比较差异有统计学意义(P＜0.05).术后3小时静脉全身麻醉组高淀粉酶血症发生率为15.5％,单纯表面麻醉组为34.5％,术后24小时静脉全身麻醉组高淀粉酶血症发生率为为5.5％,单纯表面麻醉组为19.0％.两组比较差异均有统计学意义(P＜0.05).结论 静脉全身麻醉可降低ERCP术后血清胰淀粉酶水平,减少ERCP术后胰腺炎的发生.
The effect of simple topical and intravenous general anesthesia on the occurrence of pancreatitis after ERCP surgery:a retrospective analysis
Objective To investigate the effects of simple topical anesthesia and intravenous general anesthesia on the occurrence of pancreatitis after ERCP.Methods 400 Patients who underwent ERCP due to pancreaticobiliary duct disease in our hospital from January 2021 to March 2023 were selected and divided into two groups:Simple topical anesthesia group and intravenous general anesthesia group,200 cases in each group.The levels of venous pancreatic amylase and abdominal symptoms and signs were recorded in the two groups before operation and 3 h and 24 h after operation.The observation results were hyperamylaseemia and postoperative pancreatitis at 3 h and 24 h after operation.Results The incidence of postoperative pancreatitis after ERCP was higher in the superficial anesthesia group than in the intravenous general anesthesia group(7.5％and 2.0％,respectively;P＜0.05),there was statistical significance;The level of serum pancreatic amylase(198±216)U/L in intravenous general anesthesia group was significantly lower than that in superficial anesthesia group(379±327)U/L at 3h after surgery(P＜0.05).The level of serum pancreatic amylase(129±98)U/L in intravenous general anesthesia group was lower than that in superficial anesthesia group(187±156)at 24h after surgery(P＜0.05).The incidence of hyperamylasemia was 15.5％(31/200 cases)in the 3h postoperative intravenous general anesthesia group,lower than that in the simple surface anesthesia group(34.5％)(69/200 cases),and 5.5％(11/200 cases)in the 24h postoperative intravenous general anesthesia group,lower than that in the simple surface anesthesia group(19.0％)(38/200 cases)(P＜0.05).Conclusion Compared with simple surface anesthesia,intravenous general anesthesia can reduce the level of serum amylase after ERCP,and can reduce the occurrence of pancreatitis after ERCP.

simple superficial anesthesiaintravenous general anaesthesiaendoscopic retro-grade cholangiopancreatographyhyperamylasemiapost-endoscopic retrograde cholangiopancreatogra-phy pancreatitis

张雄、杨康、高绪照、杨芳春

展开 >

416000 吉首,吉首大学医学院

湖南省张家界市人民医院肝胆外科

单纯表面麻醉 静脉全身麻醉 经内镜逆行胰胆管造影术 高淀粉酶血症 ERCP术后胰腺炎

湖北陈孝平科技发展基金

CXPJJH122002-037

2024

10.3969/j.issn.1005-6483.2024.02.014

临床外科杂志
中华医学会湖北分会

临床外科杂志

CSTPCD
影响因子：0.716
ISSN：1005-6483
年,卷(期)：2024.32(2)
  • 15