A research of the current status and influencing factors of postoperative lateral lymph node recurrence in patients with papillary thyroid carcinoma
Objective To investigate the postoperative lateral lymph node recurrence of papillary thyroid carcinoma(PTC)and its related factors.Methods The clinical and pathological data of 1 229 patients with papillary thyroid carcinoma who underwent surgery in Xiangyang Central Hospital from January 1,2018 to December 31,2022 were retrospectively collected.Results A total of 1229 patients'data were obtained,including 70 patients in the recurrence group and 1159 patients in the non-recurrence group.Multivariate COX proportional hazards regression analysis showed that tumor size(HR:0.497,95％CI:0.287-0.858),the number of primary tumors(HR:2.037,95％CI:1.209-3.433),capsular invasion(HR:0.476,95％CI:0.251-0.903),extracapsular invasion(HR:0.332,95％CI:0.169-0.657)were the influencing factors of postoperative recurrence in patients with papillary thyroid carcinoma.The proportion of central lymph node metastasis had a good predictive value in multivariate COX regression analysis(P＜0.05),and the cut-off value of the proportion of central lymph node metastasis determined by ROC curve was 23.6％.Conclusions Multiple primary lesions,tumor size＞1 cm,capsular or extracapsular extension are risk factors for recurrence of papillary thyroid carcinoma after surgery.In clinical practice,the proportion of central lymph node metastasis ≥23.6％has a good predictive effect on the risk of postoperative lateral lymph node recurrence.
万方数据
维普
