首页|创面负压治疗联合骨膜牵张术治疗糖尿病足的临床研究

创面负压治疗联合骨膜牵张术治疗糖尿病足的临床研究

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目的 探讨创面负压治疗(NPWT)联合骨膜牵张术治疗糖尿病足的临床疗效.方法 2022年6月~2023年4月我院收治的糖尿病足病人129例,采用随机数字1∶1列表法,随机分为联合组(43例)、负压组(43例)和对照组(43例),对照组采用常规治疗,负压组采用NPWT,联合组采用NPWT联合骨膜牵张技术,比较三组治疗有效率、炎性指标水平、外周血象水平、视觉疼痛(VAS)评分、足部相关指标水平.结果 治疗4周后联合组VAS评分、白细胞计数、降钙素原、白细胞介素-6、超敏C-反应蛋白均低于其他两组(P均<0.05);联合组治疗有效率、足温、趾端血氧、踝肱指数、血管内径、血流流速、灌注指数水平高于其他两组(P<0.05).结论 NPWT联合骨膜牵张术能有效缓解疼痛,改善足部血液供应,缓解机体炎性反应.
Clinical study on treatment of Diabetic foot with negative pressure of wound surface combined with periosteal distraction
Objective To explore the clinical study of the treatment of Diabetic foot with wound negative pressure treatment(NPWT)combined with periosteal distraction.Methods 129 patients with Diabetic foot admitted to our hospital from June 2022 to April 2023 were randomly divided into a combination group(n=43),a negative pressure group(n=43),and a control group(n=43).The control group was treated with conventional treatment,the negative pressure group was treated with NPWT,and the combined group was combined with periosteal distraction technique on the basis of the negative pressure group.The treatment efficiency,inflammatory index level,peripheral blood picture level,visual pain(VAS)score,and foot related index level of the three groups were compared.Results After 4 weeks of treatment,the scores of pain scale(VAS),white blood cell count(WBC),Calcitonin(PCT),Interleukin 6(IL-6),and high-sensitivity C-reactive protein(hs CRP)in the combined group were lower than those in the other two groups(P<0.05);The effective rate,foot temperature,toe blood oxygen,Ankle-brachial pressure index,vascular diameter,blood flow velocity,and perfusion index(PI)of the combined group were higher than those of the other two groups(P<0.05).Conclusion The combination of wound negative pressure therapy and periosteal distraction surgery can effectively alleviate pain,improve foot blood supply,and alleviate inflammatory reactions.

negative pressure treatment of wound surfaceperiosteal distraction surgerydiabetic foot

李静、周羿辰、衡德忠

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472000 河南省黄河三门峡医院骨科一区

创面负压治疗 骨膜牵张术 糖尿病足

三门峡市科技发展计划项目

2022002052

2024

临床外科杂志
中华医学会湖北分会

临床外科杂志

CSTPCD
影响因子:0.716
ISSN:1005-6483
年,卷(期):2024.32(7)