摘要
手术时间是影响全膝关节置换术(TKA)术后结局的重要因素,手术时间延长会导致各种不良事件的发生,最终可能引起手术失败、医疗保健成本增加甚至威胁病人的生命.手术时间延长与术后并发症的风险增加存在一定的关联.手术时间延长会增加TKA术后疼痛、伤口裂开、贫血与输血、手术区域感染、败血症、住院时间延长与再入院风险,影响假体使用寿命以及病人生存率.
Abstract
Operation duration has consistently been regarded as a important factor influencing the outcome of total knee arthroplasty(TKA).Prolonged operation time can give rise to an array of adverse events,ultimately leading to surgical failure,escalated healthcare expenses,and even jeopardizing patient survival.Numerous studies have demonstrated that prolonged operation time is linked with an augmented risk of postoperative complications.Recent investigations have revealed that extended operation duration can heighten the likelihood of postoperative pain,wound dehiscence,anemia and blood transfusion requirements,surgical site infection,sepsis,prolonged hospitalization and readmission rates;impact prosthetic longevity and patient survival rate.
基金项目
国家自然科学基金资助项目(82272251)
教育部其他项目(2021JH042)
武汉市科技局曙光计划项目(2022020801010476)
武汉大学人民医院交叉创新人才项目(JCRCYR-2022-012)
转化医学国家科学中心(上海)重点课题(SUITM-202408)