Relationship between dynamic electrocardiogram parameters and ventricular remodeling in AMI patients
Objective To investigate the relationship between 24-hour holter ECG parameters and ventricular remodeling in patients with acute myocardial infarction(AMI)and its clinical significance.Methods Ninty-eight AMI patients treated in our hospital from August 2020 to August 2021 were selected as the study objects.All patients were treated with PCI surgery after hospital.They were divided into ventricular remodeling group and non-remodeling group according to whether ventricular remodeling occurred after 6 months of treatment.The 24 h holter ECG parameters[QT variability(QTV),heart rate variability(HRV)]and left ventricular remodeling index[left ventricular end-systolic volume index were statistically compared between the two groups after 3 months and 6 months of treatment Number(LVESVI),left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume index(LVEDVI)]and serum related indicators[cardiac troponin Ⅰ(cTnⅠ),N-terminal brain pronatriuretic peptide(NT-proBNP)]levels,analyzed 24 Correlation and predictive value of hourly holter ECG parameters with ventricular remodeling.Results Compared with the non-reconstruction group,SDNN,SDANN-index,Day-QTV and Nigut-QTV in the reconstruction group were lower after 3 months and 6 months(P＜0.05).Compared with non-reconstruction group,LVESVI,LVEF and LVEDVI in reconstruction group were higher after 3 months and 6 months(P＜0.05),Compared with the non-reconstruction group,the levels of serum cTnⅠ and NT-proBNP in the reconstruction group were higher after 3 months and 6 months(P＜0.05).SDNN,SDANN-index,Day-QTV and Nigut-QTV were negatively correlated with LVESVI,LVEF,LVEDVI,cTnⅠ and NT-proBNP after 6 months in the hospital(P＜0.05).The 6-month risk of ventricular remodeling in SDNN,SDANN-index,Day-QTV and Nigut-QTV groups was 3.333,3.671,2.011 and 2.816 times higher than that in the low group,respectively(P＜0.05).Conclusions Twenty four-hour holter parameters have a pricing value for evaluating ventricular remodeling in AMI patients,which can be used to assist in assessing the degree of myocardial damage,and can be used to predict the risk of ventricular remodeling after PCI surgery,so as to carry out targeted follow-up treatment.
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