A correlation study between autonomic nervous system dysfunction and microvolt level T-wave alternation in patients with depression
Objective To explore the correlation between autonomic nervous system dysfunction and microvolt level T-wave alternation(MTWA)in patients with depression.Methods Fifty patients diagnosed with depression admitted to our hospital from January 2022 to October 2023 were selected as the research subjects.Heart rate variability(HRV),heart rate deceleration(DC),heart rate acceleration(AC),and heart rate deceleration runs(DRs)were measured to evaluate autonomic nervous system function.According to the occurrence of MTWA,they were divided into MTWA positive group and MTWA negative group.The degree of autonomic nervous system damage and possible influencing factors in the two groups of patients were compared.Use Spearman analysis to investigate the correlation between autonomic nervous system dysfunction and MTWA.Results The difference in the standard deviation of the NN(SDNN),total power(TP),high-frequency power(HF),DC,AC,DR4,and blood potassium between the MTWA positive group and the MTWA negative group was statistically significant(P＜0.05).Logistic regression analysis showed that a decrease in SDNN values is a risk factor for MTWA in patients with depression.Spearman correlation analysis showed that AC was positively correlated with MTWA,while DC,SDNN,blood potassium were negatively correlated with MTWA(P＜0.05).Conclusions There is a certain correlation between autonomic dysfunction in patients with depression and the occurrence of MTWA,which can serve as a risk indicator for predicting malignant arrhythmias and sudden cardiac death events.
DepressionAutonomic nervous system functionMicrovolt T-wave alternans
NETL
NSTL
万方数据
