[Objective]To study the risk factors of acute upper gastrointestinal bleeding in hepatitis B vi-rus(HBV)-related cirrhosis,so as to provide reference for clinical diagnosis and treatment.[Methods]A to-tal of 258 patients with HBV-related cirrhosis admitted to our hospital from July 2016 to July 2021 were retrospectively analyzed.According if they were complicated with acute upper gastrointestinal bleeding,they were divided into bleeding group(study group,142 cases)and non-bleeding group(control group,116 cases).Univariate analysis was used to analyze the risk factors of HBV-associated cirrhosis complicated with acute upper gastrointestinal bleeding,and multivariate Logistic analysis was used to further regression analysis of the above statistical data to finally explore the risk factors of HBV-associated cirrhosis compli-cated with acute upper gastrointestinal bleeding.[Results]Univariate analysis showed that liver function grade,prothrombin time,left gastric vein passage and hemoglobin were risk factors for HBV-related cirrho-sis complicated with acute upper gastrointestinal bleeding,and the differences were statistically significant(P<0.05).Multivariate analysis,which included statistical differences in the above univariate analysis,showed that liver function grade,prothrombin time,and left gastric vein passage were independent risk fac-tors for HBV-related cirrhosis with acute upper gastrointestinal bleeding.[Conclusion]Hepatic function grade,prothrombin time and left gastric vein meridian are independent risk factors for HBV-related cirrho-sis complicated with acute upper gastrointestinal bleeding.
关键词
肝硬化/乙肝病毒/急性上消化道出血/危险因素分析
Key words
related cirrhosis/hepatitis B virus/acute upper gastrointestinal bleeding/risk factor analysis