临床药师参与中枢神经系统毛霉菌感染治疗的实践及思考
Practice and experience of clinical pharmacists participating in the treatment of mucormycosis infection in central nervous system
庄伟 1齐晓涟 1高冉 2张婧 2杨毅恒 3褚燕琦 1董宪喆 1张兰1
作者信息
- 1. 首都医科大学宣武医院 药学部,北京 100053
- 2. 首都医科大学宣武医院 神经内科,北京 100053
- 3. 北京大学第三医院 药剂科,北京 100191
- 折叠
摘要
中枢神经系统毛霉菌感染是一种病情凶险的颅内感染性疾病,病死率达到50%以上.本文介绍了2例中枢神经系统毛霉菌感染危重病例,并从全身治疗药物的选择、局部治疗用药的选择及两性霉素B的用法用量、治疗疗程与序贯治疗、输注过程中的监护、发生不良反应后的对策等方面进行总结与分析,以期为临床用药提供参考.
Abstract
Mucormycosis infection of the central nervous system is a dangerous intracranial infectious disease with a mor-tality rate of over 50%.In this paper,two cases of severe Mucormycosis infection in the central nervous system were intro-duced.The selection of systemic and local drugs,the usage and dosage of amphotericin B,the course of treatment and sequen-tial treatment,the monitoring and the countermeasures after adverse reactions caused by the application of amphotericin B were summarized and analyzed to a provide reference for clinicians and pharmacists.
关键词
毛霉菌感染/两性霉素B/临床药师Key words
mucormycosis infection/amphotericin B/clinical pharmacist引用本文复制引用
出版年
2024
NETL
NSTL
万方数据