Drug fever with WBC decrease caused by voriconazole combined with imipenem and cilastatin:a case report
This article reported a case of a patient with cervical spinal cord injury and quadriplegia who developed a pul-monary infection after surgery.Fever with WBC decrease occurred after voriconazole combined with imipenem and cilastatin was administered.Clinical pharmacists consulted the literature,analyzed the relationship between the clinical symptoms and drugs,and suggested the physician stop the drugs,and then the patient's temperature and leukocytes returned to normal.This article reviewed the occurrence and treatment process of fever with WBC decrease in this case based on literature,to provide reference for physicians and pharmacists in the identification,diagnosis,treatment,and pharmaceutical care of fever with WBC decrease caused by voriconazole combined with imipenem and cilastatin.
voriconazoleimipenem and cilastatindrug feverWBC decreaseadverse drug reaction