Research progress of mitomycin C combined with internal urethrotomy in the treatment of urethral stricture
Direct vision urethral incision is currently one of the main methods for treating urethral stricture.Due to post-operative scar formation,the recurrence rate of stricture is high,and most patients need to repeat multiple surgeries.Mitomy-cin C can reduce granulation tissue and scar formation by inhibiting fibroblast proliferation.Studies have found mitomycin com-bined with internal urethrotomy for urethral stricture can greatly reduce the recurrence rate of treating urethral stricture.This ar-ticle summarizes the medication,safety,efficacy,and limitations of internal urethrotomy combined with mitomycin C through a systematic literature review,to provide reference for clinical practice.
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