A novel long-acting glucagon-like peptide-1 receptor agonist for the treatment of diabetes mellitus type 2:ecnoglutide
Glucagon-like peptide-1(GLP-1)is a class of hormone that plays a role in stimulating insulin secretion and lowering blood glucose.Ecnoglutide(research code:XW003)is a novel long-acting GLP-1 receptor agonist.The phase Ⅰand Ⅱ clinical trials have been completed,showing that ecnoglutide has a good safety and efficacy profile in treating type Ⅱdiabetes and obesity.Furthermore,the administration of the first subject has been completed in phase Ⅲ for the treatment of diabetes mellitus type 2.This article provides an overview of the ecnoglutide's basic information,mechanism of action,pre-clinical research,and clinical trials.
ecnoglutidediabetes mellitus type 2long-acting glucagon-like peptide-1 agonist