Pharmaceutical care of a chronic renal insufficiency patient with severe multisystem damage caused by medication error with low-dose methotrexate
This article reports a case of a 61-year-old female patient with a previous diagnosis of sarcoidosis and chronic renal disease who developed severe oral ulcers,severe rash,acute kidney injury,and severe myelosuppression after mistakenly taking methotrexate at 2.5 mg once daily.After hospitalization,the clinical pharmacist assisted the physician develop an individualized dosing regimen and provided pharmaceutical care,which included discontinuing methotrexate,administering folic acid for detoxification,alkalinizing the urine to promote methotrexate excretion,and symptomatic treatment for each adverse reaction.The patient improved and was discharged from the hospital.
methotrexatechronic renal insufficiencymultisystem damagepharmaceutical care
NETL
NSTL
万方数据
