Clinical comprehensive evaluation of lipid-lowering drugs in Heilongjiang Province
Objective To evaluate the lipid-regulating drugs comprehensively and provide a reference for clinical rational use of drugs and adjustment of hospital formulary.Methods A comprehensive clinical evaluation system for drugs was estab-lished using literature research,expert research,and expert argumentation.The study encompassed a comprehensive clinical evaluation of 14 lipid-lowering drugs in Heilongjiang Province across six dimensions:safety,effectiveness,economy,innova-tion,suitability,and accessibility.Results The clinical comprehensive evaluation system for lipid-lowering drugs involves 6 primary indicators and 25 secondary indicators.In terms of safety and efficacy,atorvastatin(Lipitor and Anvinin)scored the highest.In terms of economy,atorvastatin(Anvinin),rosuvastatin(Aisuning),simvastatin(Jingbisuxin),and pivastatin(Bangzhi)scored the highest;In terms of innovation,original research varieties have a greater advantage;atorvastatin(Lipitor)has the highest scores for suitability and accessibility.Conclusion Among the 14 lipid-lowering drugs in Heilongjiang Prov-ince,atorvastatin(Lipitor and Anvinin)and rosuvastatin(Keding)have higher comprehensive evaluation scores and are highly recommended varieties.
lipid-lowering drugsclinical comprehensive evaluationindicator system
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