Stevens-Johnson syndrome and toxic epidermal necrolysis induced by sintilimab treatment:a case report
This study presents a detailed analysis of a case involving a young female patient with non-small cell lung can-cer who developed Stevens-Johnson syndrome(SJS)and toxic epidermal necrolysis(TEN)after receiving her first dose of pem-brolizumab followed by single-agent chemotherapy with gemcitabine and concurrent radiotherapy.SJS/TEN caused by immu-notherapy,though rare,is associated with high mortality,and the risk may be increased with combination chemotherapy and/or radiotherapy.Therefore,caution should be exercised in selecting treatment options,and close monitoring for adverse reac-tions,as well as timely identification and management,are crucial during the treatment period.
sintilimabgemcitabineStevens-Johnson syndrome and toxic epidermal necrolysisradiation therapy
NETL
NSTL
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