Prolonged remission state of refractory adult-onset Still's disease treated with ruxolitinib combined with autologous peripheral blood stem cell transplantation:a case report
A patient with a 10-year history of adult-onset Still's disease relapsed.He developed into a critical condition after failing to respond to conventional therapy.The patient was treated with ruxolitinib plus oral steroids to control the inflam-matory storm,autologous peripheral blood stem cell transplantation was performed for immune reconstitution,and mainte-nance therapy was conducted with oral low-dose ruxolitinib after transplantation.He achieved remission for nearly 34 months.This case demonstrated the feasibility of hematopoietic stem cell transplantation followed by ruxolitinib for refractory adult Still's disease,which provided a new treatment idea for refractory patients.
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