首页|加拿大心血管病学会《临床实践更新:QT间期延长患者管理共识》解读

加拿大心血管病学会《临床实践更新:QT间期延长患者管理共识》解读

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QT间期延长是指十二导联心电图自QRS波起点到T波结束点的时间超过正常参考值范围上限而定义的一种状态。由于心电图在临床的普遍应用,医学界对QT间期的关注也越来越高。同时,我国国家药品监督管理局要求自2023年7月31日起,启动的药物临床研究相关要求适用《E14:非抗心律失常药物致QT/QTc间期延长及潜在致心律失常作用的临床评价》。因此,关于如何对QT间期延长患者进行管理成为临床关注的重要话题。2023年10月,加拿大心血管病学会发布了《临床实践更新:QT间期延长患者管理共识》,该共识对QT间期延长患者的诊断、筛查以及治疗策略给出了相关建议。本文旨在对该共识进行深入解读,分析更新内容在QT间期延长患者管理中的实践意义,并探讨其在临床工作中的应用前景。
Interpretation of the Clinical Practice Update of the Consensus on the Management of Patients with Prolonged QT Interval published by the Canadian Cardiovascular Society
Prolonged QT interval is defined as the duration from the beginning of the QRS complex to the end of the T wave on a 12-lead electrocardiogram exceeding the upper limit of the normal reference range.Due to the widespread use of clinical ECG,the medical community has paid more and more attention to QT interval.At the same time,the National Medi-cal Products Administration of China has required that E14:Clinical evaluation of QT/QTc interval prolongation and potential arrhythmogenic effects caused by non-antiarrhythmic drugs will apply to the relevant requirements of drug clinical trials starting from July 31,2023.Therefore,how to manage patients with prolonged QT interval has become an important topic in clinical concern.In October 2023,the Canadian Cardiovascular Society published the Clinical Practice Update:Consensus on the Management of Patients with Prolonged QT Interval,which provided recommendations for the diagnosis,screening and treat-ment strategies of patients with prolonged QT interval.The purpose of this article is to deeply interpret the consensus,analyze the practical significance of the updated content in the management of patients with prolonged QT interval,and explore its ap-plication prospect in clinical work.

updating clinical practiceprolonged QT intervalmanagement of patientselectrocardiogramβ receptor antagonist

刘文慧、杨青澍、常佩芬

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北京中医药大学东直门医院 心内科,北京 100700

临床实践更新 QT间期延长 患者管理 心电图 β受体拮抗剂

北京中医药大学教育科学研究课题

XJY22081

2024

临床药物治疗杂志
北京药学会

临床药物治疗杂志

CSTPCD
影响因子:1.07
ISSN:1672-3384
年,卷(期):2024.22(5)
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