Establishment and application of drug use evaluation criteria for urinary kallidinogenase
Objective To establish the drug use evaluation(DUE)criteria of urinary kallidinogenase and to provide an ef-fective and rational drug monitoring method for clinical use.Methods By referring to the drug instructions,relevant guidelines and literature,and employing the Delphi method,the urinary kallidinogenase DUE criteria was established.The DUE criteria were then applied to assess the rationality of urinary kallidinogenase for patients admitted to three hospitals in Henan Province and Shaanxi Province from March 2020 to May 2022.Results DUE criteria were established from three aspects:indications for drug use,drug use process,and drug use outcomes.A total of 456 patients were included,among which the main irratio-nal drug use phenomena included inappropriate indications(3.9%),contraindications(0.7%),inappropriate timing of medi-cation(0.9%),and drug interactions(1.8%).Conclusion The DUE criteria of urinary kallidinogenase established in this study are practical and scientific.The multi-center evaluation results showed that the clinical use of urinary kKallidinogenase is reasonable,but there are still irrational phenomena such as inappropriate indications.
urinary kallidinogenasedrug use evaluationrational drug use
NETL
NSTL
万方数据
