The article reported a case of a 48-year-old male patient who was treated with ceftazidime and avibactam sodium due to carbapenem-resistant klebsiella pneumoniae infection after renal transplantation,resulting in neutrophilic leukocytosis and thrombocytosis.After 20 days of ceftazidime avibactam sodium treatment,the patient developed a persistent abnormal increase in neutrophils and platelets.After consultation with a clinical pharmacist,the physicians were advised to discontinue the ceftazidime avibactam sodium,and then the neutrophils and platelets gradually decreased and recovered.Therefore,patients should be alert to the adverse reactions of neutrophilic leukocytosis and thrombocytosis when using ceftazidime avibactam sodium for long-term treatment,and clinical pharmacists can play an important role in pharmaceutical care.
关键词
头孢他啶阿维巴坦钠/中性粒细胞增多/血小板增多/不良反应
Key words
ceftazidime and avibactam sodium/neutrophilic leukocytosis/thrombocytosis/adverse reactions
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