Visual acuity decline caused by intravenous infusion of vancomycin:a case report
This article reported a case of a 63-year-old male patient who was initially treated with vancomycin combined with meropenem for infective endocarditis in another hospital.After 9 days,the patient's condition improved.However,due to insufficient antimicrobial therapy,he was transferred to our hospital,where vancomycin was continued.After 8 days of treatment,the patient developed blurred vision and decreased visual acuity,which was considered to be caused by vancomycin.The clinical pharmacist advised discontinuation of vancomycin and the patient was switched to linezolid and tobramycin dexamethasone eye drops were administered.The above symptoms improved after 2 days of drug withdrawal and returned to normal after 10 days of drug withdrawal.Although ocular adverse reactions to intravenous vancomycin infusion are rare,they can lead to serious consequences,and clinical attention should be paid to improve drug safety.
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