基于万古霉素血药浓度监测治疗感染性心内膜炎的药学实践一例
A case of pharmaceutical practice in the treatment of infective endocarditis based on vancomycin therapeutic drug monitoring
谢媛 1任俊 1赵静 1陈玉艳1
作者信息
- 1. 联勤保障部队第九四〇医院 药剂科,兰州 730050
- 折叠
摘要
本文介绍临床药师参与1例感染性心内膜炎患者的治疗过程.临床药师结合万古霉素血药浓度监测结果及国内外指南推荐调整用药方案后,万古霉素血药浓度达到目标浓度范围,患者感染指标得到改善,同时肌酐、尿素值等均在正常范围.提示临床药师基于血药浓度的个体化用药方案的调整,有助于耐甲氧西林金黄色葡萄球菌所致严重感染的及时控制.
Abstract
This paper presents a case of clinical pharmacist's involvement in the treatment of infective endocarditis.After pharmacists adjusted the dosing regimen based on the plasma concentration of vancomycin and recommendations of domestic and foreign guidelines,the plasma concentration of vancomycin reached the target range,and the infection of the patient was well controlled.During the process,the creatinine and urea values were in the normal range.This case highlights the importance of individualized drug regimen adjustments based on therapeutic drug monitoring,which can aid in the timely control of serious infections caused by methicillin-resistant staphylococcus aureus.
关键词
万古霉素/血药浓度监测/感染性心内膜炎/药学实践Key words
vancomycin/therapeutic concentration monitoring/infective endocarditis/pharmaceutical practice引用本文复制引用
出版年
2024
NETL
NSTL
万方数据