Analysis of Treatment Strategies in the"2023 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke"
The"2023 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke"(referred to as the new guidelines)have comprehensively updated the diagnostic and treatment strategies for acute ischemic stroke,with the aim of optimizing patient treatment strategies,improving therapeutic outcomes,and reducing disability and mortality rates.Adhering to the principle of individualized treatment,the new guidelines introduce a series of innovative approaches.Notably,the incorporation of the novel thrombolytic agent tenecteplase and the extension of the therapeutic time window mark significant advancements in vascular recanalization therapy.Furthermore,the new guidelines encompass multiple crucial aspects,including life support and basic management,antiplatelet therapy,anticoagulant therapy,rehabilitation therapy,and the management of acute-phase complications.Specifically,in the domain of life support and basic management,the new guidelines emphasize individualized management strategies for respiratory function,cardiac care,temperature control,blood pressure regulation,and glycemic control.In the realm of vascular recanalization therapy,not only is tenecteplase introduced as a new therapeutic option,but the latest advancements in endovascular interventional therapy are also detailed,thereby broadening the spectrum of treatment possibilities.Regarding antiplatelet and anticoagulant therapy,the new guidelines provide more refined treatment algorithms and underscore the importance of individualized assessment and tailored therapy.In the area of rehabilitation therapy,the new guidelines highlight the profound positive impact of early rehabilitation on patient outcomes.For the management of acute-phase complications,the new guidelines offer specific and evidence-based recommendations for addressing common complications such as cerebral edema,seizures,pneumonia,and deep vein thrombosis.Compared to previous guidelines both domestically and internationally,the new guidelines maintain consistency while demonstrating Chinese characteristics and an innovative spirit.By following the recommendations of the new guidelines,clinicians can more accurately select treatment options,leading to better patient outcomes.This article provides an analysis of the treatment strategies outlined in the new guidelines.