Research progress on quality control of alfacalcitol
Alfacalcidol,an active metabolite of vitamin D3,is mainly used in clinical practice for various symptoms caused by osteoporosis and abnormal vitamin D metabolism.It has the characteristics of rapid onset,wide application range and high safety.With the deepening of research on alfacalcidol,a variety of dosage forms have been developed,and the quality standards have been continuously improved.Therefore,this study conducted a comprehensive literature review by systematically searching PubMed,UpToDate,CNKI,Wanfang databases and other databases.This review focused on elucidating pharmacological mechanism,the quality control research,and safety of alfacalcidol.The objective was to establish a foundation for further quality standard research of alfacalcitol and provide a reliable reference.