临床药师参与儿童放线菌胸部脓肿的抗感染治疗一例
Clinical pharmacists participated in the anti-infective treatment of actinomycete chest abscess in children:a case report
黄秀琼 1李梦 2曹忠强 2彭佼 3王元祥 4李学娟2
作者信息
- 1. 肇庆市第一人民医院 药学部,广东 肇庆 526000
- 2. 深圳市儿童医院 药剂科,广东 深圳 518000
- 3. 北京大学深圳医院 药学部,广东 深圳 518036
- 4. 深圳市儿童医院心胸外科,广东 深圳 518000
- 折叠
摘要
本文报道临床药师参与1例儿童放线菌胸部脓肿的抗感染治疗过程.临床药师基于循证依据,根据患儿疾病特点,结合病原体的流行病学特点、抗菌药物的杀菌活性等,将抗菌谱广、级别高的头孢哌酮钠舒巴坦钠降阶梯为抗菌谱窄、疗效确切的青霉素,并对出院带药的选择和疗程进行评估,以及对出院后患儿发生的药物不良反应进行评估并调整用药方案,通过全过程药学监护,实现精准用药,保障患儿治疗效果.本例患儿的抗感染治疗及药学监护为该类疾病的临床治疗提供参考.
Abstract
This article reported a case of a clinical pharmacist participating in the anti-infective treatment process of actinomycete chest abscess in a pediatric patient.Based on evidence-based medicine,the characteristics of the patient's condition,the epidemiological characteristics of pathogens,and the bactericidal activity of antibiotics,clinical pharmacists suggested de-escalating from cefoperazone sodium and sulbactam sodium which was a high-level antibiotic with wide antibacterial spectrum to penicillin which is am antibiotic with narrow antibacterial spectrum but with definite curative effect.At discharge,the choice of maintenance antibiotic and the duration of anti-infective therapy was evaluated and recommended.Furthermore,the therapy regimen was adjusted because of the occurrence of adverse drug reactions after discharge.Through full-process pharmaceutical monitoring,precise medicationwas achieved to ensure the efficiency and safety of the pediatric patient.The anti-infective treatment and pharmaceutical monitoring of the patient in this case could provide references for the clinical treatments of similar cases.
关键词
胸部脓肿/放线菌/抗感染治疗/药学监护/临床药师Key words
chest abscess/actinomycete/anti-infective treatment/pharmaceutical monitoring/clinical pharmacists引用本文复制引用
出版年
2024
NETL
NSTL
万方数据