摘要
药物经济性评价是应用经济学、流行病学、生物统计学等多学科研究方法,比较不同药物或治疗方案的成本、效益或效果及效用,评价其经济学价值差异.药物经济学评价结果被众多国家用于药械目录准入及调控、药品费用调控、药品价格制定,以及医疗保险报销赔付等领域,对提高医疗卫生资源的配置效率起到重要作用.药物经济性评价应该包括明确研究问题、适用性评价、时效性评价及方法学质量评价等重要步骤.本章旨在针对药品综合评价过程中,利用已产生的药物经济学结果及相关信息资料对药物经济性进行快速评估.对相关要素和评价框架作出推荐,对临床用药过程中经济性判定提供相关依据和思路方法.
Abstract
Economic evluation of medicines involves the application of multidisciplinary research methods including economics,epidemiology,and biostatistics to compare the costs,benefits,effects and utility of different treatment plans,thereby assessing their economic value.The results of pharmacoeconomic evaluation have been widely used by many countries for drug formulary inclusion,cost regulation,price formulation,and medical insurance reimbursement and compensation,playing an important role in improving the efficiency of medical and health resource allocation.The economic evaluation of medicines includes important steps such as defining research questions,assessing applicability and timeliness,and evaluating methodological quality.This chapter aims to describe the methods of utilizing the findings of pharmacoeconomics assessment and relevant information to quickly evaluate the economic viability of drugs in the process of comprehensive drug evaluation.Relevant elements and evaluation frameworks are recommended,while the foundation and methods for economic decision-making in clinical medication process are also provided.