Application value of high-resolution CT in the differential diagnosis of benign and malignant pulmonary ground glass nodules
Objective To analyze the value of high-resolution CT in the differential diagnosis of benign and malignant pulmonary ground glass nodules(GGN).Methods A total of 106 patients with GGN admitted to the Ninth People's Hospital of Zhengzhou from February 2021 to February 2023 were selected.All patients underwent high-resolution CT examination,with pathological examination as the"gold standard".The value of high-resolution CT in differencetial diagnosis of benign and malignant GGN was analyzed.Additionally,the differences in high-resolution CT related features of GGN with different properties were compared.Results Among the 106 GGN patients,75 patients were found to be malignant and 31 patients were found to be benign according to the pathological examination.A total of 73 cases of malignancy were detected by high-resolution CT.Using pathological examination as the"gold standard",the sensitivity of high-resolution CT in diagnosing malignant GGN was 94.67％(71/75),the specificity was 93.55％(29/31),and the accuracy was 98.11％(104/106).The kappa test showed excellent consistency between the high-resolution CT examination results and the"gold standard"examination results(kappa value=0.866,P＜0.001).There was no significant difference in the proportion of lesion morphology,bronchial sign,vacuolar sign,pleural indentation sign,and vascular bundle sign between benign and malignant GGN patients(P＞0.05).The proportion of lobulation sign and spicule sign in malignant GGN patients was higher than that in benign GGN patients,and the differences were significant(P＜0.05).Conclusions High resolution CT can effectively differentiate and diagnose GGN patients,and there are significant differences in the examination related signs of different types of GGN patients.
Pulmonary ground glass nodulesHigh resolution CTBenign and malignantSign
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