首页|实时心肌声学造影联合左心室压力-应变环技术评估急性心肌梗死介入治疗后患者心肌再灌注的价值

实时心肌声学造影联合左心室压力-应变环技术评估急性心肌梗死介入治疗后患者心肌再灌注的价值

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目的 探讨实时心肌声学造影(RT-MCE)联合左心室压力-应变环技术(PSL)评估急性心肌梗死(AMI)介入治疗后患者心肌再灌注的价值。方法 选择2021年1月至2022年2月驻马店市中心医院行经皮冠状动脉介入术(PCI)的108例AMI患者为研究对象。在患者PCI术后行RT-MCE和超声心动图PSL检查,以术后冠状动脉造影为金标准,根据造影后TIMI血流分级评估患者心肌再灌注情况,将患者分为无复流(NR)组和非NR组,比较两组RT-MCE参数及PSL参数,绘制受试者工作曲线(ROC曲线),分析RT-MCE参数联合PSL参数对AMI患者PCI术后心肌灌注的评估价值。结果 经冠状动脉造影检查结果显示,PCI后108例AMI患者中有81例患者心肌灌注正常,占比75%,纳入非NR组;27例患者发生心肌灌注异常,占比25%,其中TIMI Ⅰ级23例,TIMI 0级4例,纳入NR组。NR组患者心肌显影强度(A)、微泡破坏后再充盈的血流速度(β)、心肌血流量(A × β)水平均明显低于非NR组,差异有统计学意义(P<0。05);NR组二维左心室整体纵向应变、心肌整体做功指数、整体做功效率、整体有用功水平明显低于非NR组,整体无用功水平高于非NR组,差异有统计学意义(P<0。05);绘制ROC曲线,结果显示,RT-MCE参数联合PSL参数评估AMI患者PCI术后心肌灌注异常的AUC>0。7。结论 RT-MCE联合PSL技术在AMI患者介入治疗后心肌灌注评估中具有一定应用价值。
Value of real-time myocardial contrast echocardiography combined with left ventricular pressure-strain loop technique in evaluating myocardial reperfusion in patients with acute myocardial infarction after interventional treatment
Objective To investigate the value of real-time myocardial contrast echocardiography(RT-MCE)combined with left ventricular pressure-strain loop(PSL)in evaluating myocardial reperfusion in patients with myocardial infarction(AMI)after interventional treatment.Methods A total of 108 AMI patients who underwent percutaneous coronary intervention(PCI)at Zhumadian Central Hospital from January 2021 to February 2022 were included as the study subjects.After PCI,the patients underwent RT-MCE and echocardiography PSL examinations.Postoperative coronary angiography was taken as the gold standard,myocardial reperfusion was evaluated based on the TIMI blood flow grading after angiography.The patients were divided into a non reflow(NR)group and a non NR group.The RT-MCE parameters and PSL parameters were compared between the two groups,and the receiver operating curve(ROC curve)was drawn to analyze the evaluation value of RT-MCE parameters combined with PSL parameters on myocardial perfusion after PCI in AMI patients.Results According to the results of coronary angiography,81 patients out of 108 AMI patients after PCI had normal myocardial perfusion,accounting for 75%,who were enrolled in the non NR group;27 patients experienced myocardial perfusion abnormalities,accounting for 25%,including 23 cases with TIMI grade Ⅰ and 4 cases with TIMI grade 0,who were enrolled in the NR group.The levels of myocardial imaging intensity(A),the bloodflow velocity of refilling after microbubble destruction(β)and myocardial blood flow(A×β)in NR group were significantly lower than those in non NR group,with significant differences(P<0.05).The two-dimensional global longitudinal peak stain,global work index,global work efficiency,global constuctive work levels in the NR group were significantly lower than those in the non NR group,while the global waste work levels were higher than those in the non NR group,with significant differences(P<0.05).The ROC curve was plotted,and the results showed that the AUC of RT-MCE parameters combined with PSL parameters for evaluating myocardial perfusion abnormalities in AMI patients after PCI was greater than 0.7.Conclusions RT-MCE combined with PSL technology has certain value in evaluating myocardial perfusion in AMI patients after interventional therapy.

Acute myocardial infarctionPercutaneous coronary interventionReal-time myocardial contrast echocardiographyLeft ventricular pressure-strain loop techniqueMyocardial perfusion

雷媛媛

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河南省驻马店市中心医院超声科 463000

急性心肌梗死 经皮冠状动脉介入术 实时心肌声学造影 左心室压力-应变环技术 心肌灌注

2024

临床医学
中华医学会河南分会

临床医学

影响因子:0.906
ISSN:1003-3548
年,卷(期):2024.44(3)
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