Value of real-time myocardial contrast echocardiography combined with left ventricular pressure-strain loop technique in evaluating myocardial reperfusion in patients with acute myocardial infarction after interventional treatment
Objective To investigate the value of real-time myocardial contrast echocardiography(RT-MCE)combined with left ventricular pressure-strain loop(PSL)in evaluating myocardial reperfusion in patients with myocardial infarction(AMI)after interventional treatment.Methods A total of 108 AMI patients who underwent percutaneous coronary intervention(PCI)at Zhumadian Central Hospital from January 2021 to February 2022 were included as the study subjects.After PCI,the patients underwent RT-MCE and echocardiography PSL examinations.Postoperative coronary angiography was taken as the gold standard,myocardial reperfusion was evaluated based on the TIMI blood flow grading after angiography.The patients were divided into a non reflow(NR)group and a non NR group.The RT-MCE parameters and PSL parameters were compared between the two groups,and the receiver operating curve(ROC curve)was drawn to analyze the evaluation value of RT-MCE parameters combined with PSL parameters on myocardial perfusion after PCI in AMI patients.Results According to the results of coronary angiography,81 patients out of 108 AMI patients after PCI had normal myocardial perfusion,accounting for 75%,who were enrolled in the non NR group;27 patients experienced myocardial perfusion abnormalities,accounting for 25%,including 23 cases with TIMI grade Ⅰ and 4 cases with TIMI grade 0,who were enrolled in the NR group.The levels of myocardial imaging intensity(A),the bloodflow velocity of refilling after microbubble destruction(β)and myocardial blood flow(A×β)in NR group were significantly lower than those in non NR group,with significant differences(P<0.05).The two-dimensional global longitudinal peak stain,global work index,global work efficiency,global constuctive work levels in the NR group were significantly lower than those in the non NR group,while the global waste work levels were higher than those in the non NR group,with significant differences(P<0.05).The ROC curve was plotted,and the results showed that the AUC of RT-MCE parameters combined with PSL parameters for evaluating myocardial perfusion abnormalities in AMI patients after PCI was greater than 0.7.Conclusions RT-MCE combined with PSL technology has certain value in evaluating myocardial perfusion in AMI patients after interventional therapy.