Characteristics of endometrial lesions and significance of diagnostic curettage in women aged 25～55 years
Objective To investigate the characteristics of endometrial lesions in women aged 25～55 years and the significance of diagnostic curettage.Methods A total of 150 patients aged 25～55 with suspected endometrial lesions admitted to the Second People's Hospital of Jiaozuo from January 2019 to December 2021 were selected as the study subjects.All patients underwent diagnostic curettage under hysteroscopy,with postoperative pathological biopsy as the gold standard.The diagnostic results and efficacy of diagnostic curettage were analyzed,and the characteristics of female endometrial lesions were studied.Results The 150 suspected patients with endometrial lesions were confirmed to have normal endometrium in 45 cases(30.00％,45/150),endometrial polyps in 64 cases(42.67％,64/150),endometrial hyperplasia in 32 cases(21.33％,32/150),endometrial cancer in 5 cases(3.33％,5/150),and submucosal fibroids in 4 cases(2.67％,4/150)through pathological examination.Among the 150 suspected patients with endometrial lesions,postoperative pathological biopsies showed positive results in 105 cases and negative results in 45 cases.After diagnostic curettage,89 cases were positive and 41 cases were negative.The 150 suspected patients with endometrial lesions were diagnosed with a sensitivity of 84.76％(89/105),specificity of 91.11％(41/45),accuracy of 86.67％(130/150),misdiagnosis rate of 8.89％(4/45),and missed diagnosis rate of 15.24％(16/105)through diagnostic curettage.The diagnostic curettage revealed 53 cases of endometrial polyps,8 cases of submucosal fibroids,38 cases of endometrial hyperplasia,5 cases of endometrial cancer,and 46 cases of normal endometrium.The diagnostic accuracy of diagnostic curettage for patients with endometrial lesions was 86.67％(130/150),and 150 cases showed endometrial thickening through diagnostic curettage,but pathological examination showed ordinary hyperplasia or endocrine phase changes.Conclusions Diagnostic curettage applied to women aged 25-55 with endometrial lesions has high sensitivity and accuracy,which can reduce misdiagnosis and missed diagnosis,and can reflect the characteristics of female endometrial lesions.
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