首页|高龄剖宫产孕妇产前血浆纤维蛋白原及血栓弹力图参数对产后出血的预测价值

高龄剖宫产孕妇产前血浆纤维蛋白原及血栓弹力图参数对产后出血的预测价值

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目的 探讨高龄剖宫产孕妇产前血浆纤维蛋白原(Fib)与血栓弹力图参数联合预测产后出血的价值。方法 选择2021年10月至2023年10月新乡市中心医院收治的高龄剖宫产孕妇104例进行研究,产前均予以血浆Fib、血栓弹力图参数预测产后出血情况,将产后实际情况作为标准,评价血浆Fib、血栓弹力图参数及二者联合预测结果,同时对比产后出血组与非产后出血组凝血指标、血栓弹力图参数。结果 104例高龄剖宫产孕妇产后实际发生产后出血(阳性)54例、非产后出血(阴性)50例,血浆Fib产前预测阳性40例、阴性64例,血栓弹力图参数产前预测阳性44例、阴性60例,二者联合产前预测阳性51例、阴性53例。二者联合产前预测效能在准确度、灵敏度上高于血浆Fib、血栓弹力图参数预测(P<0。05)。产后出血组Fib水平明显低于非产后出血组,差异有统计学意义(P<0。05),但其余指标比较,差异未见统计学意义(P>0。05)。产后出血组与非产后出血组血栓弹力图参数比较,前者凝固时间(K)更短,血栓最大幅度(MA)更低,差异有统计学意义(P<0。05),其余参数两组比较,差异未见统计学意义(P>0。05)。结论 高龄剖宫产孕妇产后出血预测方法中采取产前血浆Fib联合血栓弹力图参数预测,有着良好的预测价值,其预测效能高(准确度与灵敏度高),而且还可结合产前血浆Fib水平、血栓弹力图参数中的K、MA值异常情况来辅助判断,从而为临床预测产后出血提供依据。
Predictive value of prenatal plasma fibrinogen and thrombus elastogram parameters for postpartum hemorrhage in elderly women with cesarean section
Objective To study the predictive value of prenatal plasma fibrinogen(Fib)and thrombus elastogram parameters for postpartum hemorrhage in elderly women with cesarean section.Methods A total of 104 elderly pregnant women with cesarean section in the Central Hospital of Xinxiang were selected for this study.Before delivery,plasma Fib and thromboxogram parameters were used to predict postpartum hemorrhage.The actual postpartum situation was taken as the standard to evaluate the parameters of plasma Fib and thromboxogram and their combined prediction results,and coagulation indexes and thromboxogram parameters were compared between the postpartum hemorrhage group and the non-postpartum hemorrhage group.Results Among the 104 elderly pregnant women with cesarean section,postpartum hemorrhage(positive)occurred in 54 cases,non-postpartum hemorrhage(negative)in 50 cases,plasma Fib prenatal prediction was positive in 40 cases and negative in 64 cases,thrombologram parameters prenatal prediction was positive in 44 cases and negative in 60 cases,and the combined prenatal prediction was positive in 51 cases and negative in 53 cases.The accuracy and sensitivity of the combined prenatal prediction were higher than those of plasma Fib and thromboelastogram parameters(P<0.05).The Fib of postpartum hemorrhage group was significantly lower than that of non-postpartum hemorrhage group(P<0.05),but there was no significant difference in other indexes(P>0.05).Compared with the non-postpartum hemorrhage group,the K value of the postpartum hemorrhage group was higher and the MA value was lower,the differences were significant(P<0.05),and the other parameters were not significantly different between the two groups(P>0.05).Conclusions Prenatal plasma Fib combined with thromboelastogram parameters has good prediction value for postpartum hemorrhage in elderly women with cesarean section,and its prediction efficiency is high(high accuracy and sensitivity),and prenatal plasma Fib level and the abnormal K and MA values in thromboelastogram parameters can also be combined to assist judgment,so as to provide a basis for clinical prediction of postpartum hemorrhage.

Aged cesarean sectionPlasma fibrinogenThromboelastogram parametersPostpartum hemorrhagePredictive effectiveness

李莉

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河南省新乡市中心医院新乡医学院第四临床学院 453000

高龄剖宫产 血浆纤维蛋白原 血栓弹力图参数 产后出血 预测效能

2024

临床医学
中华医学会河南分会

临床医学

影响因子:0.906
ISSN:1003-3548
年,卷(期):2024.44(5)
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