Comparison of efficacy of single and two-port thoracoscopic lobectomy combined with systemic lymph node dissection in the treatment of lung cancer
Objective To compare the efficacy of single-port and two-port thoracoscopic lobectomy(TPTL)combined with systemic lymphadenectomy(SL)on lung cancer.Methods A total of 86 patients with lung cancer admitted to Henan Chest Hospital from February 2020 to February 2023 were selected as the study objects.They were divided into control group and observation group according to random number table method,with 43 cases in each group.The control group was treated with two-port thoracoscopic lobectomy combined with systemic lymph node dissection,and the observation group was treated with single-port thoracoscopic lobectomy combined with systemic lymph node dissection.The two groups were compared in the perioperative period(operation time,blood loss,number of lymph node removal,drainage volume,hospitalization days),visual analogue score(VAS),stress indexes[prostaglandin E2(PGE2),norepinephrine(NE),cortisol(Cor)]levels,lung function[forced respiratory volume in the first second(FEV1),forced vital capacity(F VC)]levels and complications.Results The observation group had shorter operation time,less bleeding,more lymph node dissection,and more drainage compared to the control group(P＜0.05).After 24 hours and 72 hours of surgery,the VAS score of the observation group was lower than that of the control group(P＜0.05).At 72 hours after surgery,the PGE2,NE,and Cor levels in the observation group were lower than those in the control group,while the levels of FEV1 and FVC were higher than those in the control group(P＜0.05).There was no significant difference in the incidence of complications between the two groups(P＞0.05).Conclusions Compared with two-port TPTL and SL treatment,single port thoracoscopic lobectomy and SL treatment can reduce surgical trauma and stress response,alleviate pain,promote lung function recovery,which has better safety.
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