Clinical study of laparoscopic hepatectomy for primary liver cancer with different hepatic flow blocking techniques
Objective To analyze the clinical effects of laparoscopic hepatectomy with different hepatic blood flow blocking techniques on primary liver cancer.Methods A total of 80 patients with primary liver cancer in the Second People's Hospital of Jiaozuo from January 2020 to October 2023 were selected and divided into experimental group and control group according to random number table method,with 40 cases in each group.The control group underwent blood flow blockade by Pringle method,and hemihepatic vascular control(HVC)was used in the experimental group.The perioperative parameters(blocking time,intraoperative blood loss,blood transfusion,hospital stay,operation time),liver function[alanine aminotransferase(ALT),aspartate aminotransferase(AST),albumin(ALB)]AST),intestinal mucosal barrier(endotoxin,D-lactic acid)and complication rate were compared between the two groups.Results Compared with the control group,the experimental group had less blood loss and blood transfusion,and the operation time and hospitalization days were shorter(P＜0.05).Compared with the control group,the levels of ALT,ALB and AST in experimental groups were lower at 3 and 7 days after surgery(P＜0.05).Compared with the control group,the levels of endotoxin and D-lactic acid in experimental group were lower at 7 days after operation(P＜0.05).There was no significant difference in the complication rate between the experimental group[(5.00％(2/40)]and the control group[15.00％(6/40)](P＞0.05).Conclusions HVC block technique in the treatment of primary liver cancer patients with laparoscopic hepatectomy can reduce the surgical trauma,reduce the damage to liver function and the damage of intestinal mucosal barrier,and this protocol has a high treatment safety.
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