首页|球囊扩张联合取栓术治疗颅内动脉狭窄合并急性闭塞的效果观察

球囊扩张联合取栓术治疗颅内动脉狭窄合并急性闭塞的效果观察

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目的 探讨球囊扩张联合取栓术治疗颅内动脉狭窄合并急性闭塞的临床效果。方法 选取2019年3月至2022年9月驻马店市第一人民医院收治的121例颅内动脉狭窄合并急性闭塞患者为研究对象。根据治疗方式分为研究组与对照组。研究组60例,采用介入吸栓联合球囊扩张治疗;对照组61例,采用常规支架取栓治疗。比较两组患者的术后血管再通率、手术前后血流动力学指标[纤维蛋白原、血浆黏度(PV)、全血高切黏度及全血低切黏度]、治疗前后的神经功能[美国国立卫生院卒中量表(NIHSS)]。结果 研究组的血管再通率(83。3%,38/61)较对照组(62。3%,50/60)高(P<0。05)。术前,两组的血流动力学指标比较,差异未见统计学意义(P>0。05),而术后两组的血流动力学指标均较术前改善,且研究组优于对照组(P<0。05)。术前两组的神经功能比较,差异未见统计学意义(P>0。05),而术后两组的神经功能均较术前改善,且研究组优于对照组(P<0。05)。结论 介入吸栓联合球囊扩张对颅内动脉狭窄合并急性闭塞患者的疗效较佳,可以提高血管再通率、改善其血流动力学指标及神经功能。
Curative effect of balloon dilation combined with thrombectomy on intracranial artery stenosis with acute occlusion
Objective To investigate the effect of balloon dilation combined with thrombectomy on intracranial artery stenosis with acute occlusion.Methods A total of 121 patients with intracranial artery stenosis with acute occlusion in Zhumadian First People's Hospital from March 2019 to September 2022 were selected as the study objects.According to the treatment methods,they were divided into study group and control group.In the study group,60 cases were treated with interventional thrombolysis combined with balloon expansion.In the control group,61 cases were treated with conventional stent thrombectomy.The postoperative vascular revascularization rate,the hemodynamic indexes[fibrinogen,plasma viscosity(PV),whole blood high tangential viscosity and whole blood low tangential viscosity]before and after surgery,the neurological function before and after treatment[National Institutes of Health Stroke Scale(NIHSS)].Results The vascular revascularization rate in the study group(83.3%,38/61)was higher than that in the control group(62.3%,50/60)(P<0.05).Before surgery,there was no significant difference in the hemodynamic indexes between the two groups(P>0.05),but after surgery,the hemodynamic indexes of the two groups were improved compared with the preoperative ones,and the study group was more improved than the control group(P<0.05).There was no significant difference in neurological function between the two groups before surgery(P>0.05),but the neurological function of the two groups was improved after surgery,and the study group was more improved than the control group(P<0.05).Conclusions Interventional thrombolysis combined with balloon dilatation has a better effect on intracranial artery stenosis with acute occlusion,which can not only improve the vascular revasculation rate,but also improve the hemodynamic indexes and the neurological function.

Interventional aspiration and extractionBalloon dilatationIntracranial arterial stenosis with acute occlusion

王星淳、剧新杰、刘锦辉

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河南省驻马店市第一人民医院神内三科 463000

介入吸栓取栓 球囊扩张 颅内动脉狭窄合并急性闭塞

2024

临床医学
中华医学会河南分会

临床医学

影响因子:0.906
ISSN:1003-3548
年,卷(期):2024.44(9)