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消风散结汤加减治疗小儿腺样体肥大的效果

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目的 分析消风散结汤加减治疗小儿腺样体肥大的效果。方法 选择2022年8月至2023年9月信阳市中医院收治的8 0例小儿腺样体肥大患儿为研究对象,按照随机数字表法分为对照组与观察组,每组40例。对照组采用常规西医治疗,观察组在对照组基础上采用消风散结汤加减治疗。比较两组临床效果、中医证候积分、鼻咽部X线积分、嗜酸粒细胞(EOS)、嗜酸性粒细胞趋化因子(Eotaxin)、白细胞介素-4(IL4)、肿瘤坏死因子-α(TNF-α)及复发率。结果 观察组患者总有效率[97。50%(39/40)]较对照组患者[80。00%(32/40)]高(P<0。05)。观察组患者治疗后鼻塞、打鼾、张口呼吸评分均较对照组患者低(P<0。05)。观察组患者治疗后鼻咽部X线积分较对照组患者低(P<0。05)。观察组患者治疗后EOS、Eotaxin水平较对照组患者低(P<0。05)。观察组患者治疗后IL-4、TNF-α水平较对照组患者低(P<0。05)。观察组患者复发率[5。13%(2/39)]较对照组患者[25。00%(8/32)]低(P<0。05)。结论 消风散结汤加减治疗小儿腺样体肥大,可减轻炎性反应和变态反应,能改善临床症状,提高疗效,并可降低复发率。
Effect of modified Xiaofeng Sanjie decoction on children with adenoid hypertrophy
Objective To analyze the effect of modified Xiaofeng Sanjie decoction on children with adenoid hypertrophy.Methods A total of 80 children with adenoid hypertrophy treated in Xinyang Hospital of Traditional Chinese Medicine from August 2022 to September 2023 were selected as the study objects,and were divided into observation group and control group according to random number table method,with 40 cases in each group.The control group adopted conventional western medicine treatment,and the observation group adopted Xiaofeng Sanjie decoction on the basis of control group.The clinical effect,TCM syndrome score,nasopharyngeal X-ray score,EOS,Eotaxin,interleukin-4(IL-4),tumor necrosis factor α(TNF-α)and recurrence rate of two groups were compared.Results The total effective rate of observation group[97.50%(39/40)]was higher than that of control group[80.00%(32/40)](P<0.05).After treatment,the scores of nasal congestion,snoring and open mouth breathing in observation group were lower than those in control group(P<0.05).The nasopharyngeal X-ray score of observation group was lower than that of control group(P<0.05).After treatment,the levels of EOS and Eotaxin in observation group were lower than those in control group(P<0.05).The levels of IL-4 and TNF-α in observation group were lower than those in control group after treatment(P<0.05).The recurrence rate of observation group[5.13%(2/39)]was lower than that of control group[25.00%(8/32)](P<0.05).Conclusions Xiaofeng Sanjie decoction in the treatment of children with adenoid hypertrophy can reduce inflammatory reaction and allergic reaction,improve the clinical symptoms and curative effect,and reduce the recurrence rate.

Children with adenoid hypertrophyXiaofeng Sanjie decoctionEffect

梁丽娜

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河南省信阳市中医院儿科 464000

小儿腺样体肥大 消风散结汤 效果

河南省中医药传承与创新人才工程(仲景工程)中医药拔尖人才自主项目

豫卫中医涵[2021]15号

2024

临床医学
中华医学会河南分会

临床医学

影响因子:0.906
ISSN:1003-3548
年,卷(期):2024.44(9)