Comparison of the efficacy of neuroendoscopic keyhole approach and craniotomy on hypertensive cerebral hemorrhage
Objective To compare the clinical effects of neuroendoscopic keyhole approach and craniotomy on hypertensive cerebral hemorrhage.Methods A total of 80 patients with hypertensive cerebral hemorrhage admitted to the Department of Neurosurgery of Anyang People's Hospital from June 2020 to December 2023 were selected as the study objects.According to the operation method,the patients were divided into observation group and control group,with 40 cases in each group.The observation group was treated with neuroendoscopic keyhole approach,and the control group was treated with craniotomy.The clinical efficacy,operation related indexes(operation time,intraoperative blood loss,and hematoma volume hematoma before and after operation),neurological deficit score,serum levels of lipoprotein-associated phospholipase A2(LP-PLA2)and glial fibrillary acidic protein(GFAP)and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group(P＜0.05).The operative time and intraoperative blood loss in the observation group were significantly lower than those in control group(P＜0.05),and the hematoma volume after operation was lower than that in the control group,and the clearance rate of hematoma was higher than that in the control group(P＜0.05).Before treatment,there was no significant difference in neurological function deficit score and the levels of LP-PLA2 and GFAP between the two groups(P＞0.05).After treatment,the neurological impairment scores of both groups were significantly lower than those before treatment,and the levels of LP-PLA2 and GFAP were lower than those before treatment(P＜0.05),and those of the observation group was significantly lower than those of the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions Neuroendoscopic keyhole approach can significantly improve the therapeutic effect on hypertensive intracerebral hemorrhage,and reduce the levels of LP-PLA2 and GFAP in blood.
Neuroendoscopic keyhole approachCraniotomyHypertensive cerebral hemorrhageLipoprotein-associated phospholipase A2Glial fibrillary acidic protein
NETL
NSTL
万方数据
