首页|An Update on Treatment of Drug-Induced Liver Injury

An Update on Treatment of Drug-Induced Liver Injury

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Drug-induced liver injury (DILI) has been linked to more than 1,000 medications and remains the most common cause of acute liver failure in the United States. Here, we review the most current literature regarding treatment and make recommendations for the management of this relatively common disease. Since treatment of DILI remains largely elusive, recent studies have attempted to define new management strategies for these difficult patients. Early diagnosis and withdrawal of the suspected medication is the mainstay of treatment of DILI. For acetaminophen and Amanita mushroom poisoning, there are specific therapies in use. Finally, there are other possible management mod-alities for DILI, including corticosteroids and ursodeoxycholic acid.

Drug-induced liver injuryHepatotoxicityAcetaminophen toxicity

Christin Giordano、John Rivas、Xaralambos Zervos

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Department of Faculty and Academic Affairs, University of Central Florida, College of Medicine, Orlando, FL, USA

Digestive Disease Institute, Cleveland Clinic Florida, Weston, FL, USA

2014

10.14218/JCTH.2014.00005

临床与转化肝病杂志(英文版)

临床与转化肝病杂志(英文版)

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年,卷(期)：2014.2(2)
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